Cosmetics in vivoDemonstrate the Efficacy of your Final Product or Ingredient
Anti-wrinkles and Anti-acne
Through a new high resolution 3D imaging technology, we generate a HR 3D image of the skin surface and quantify the capacity of a treatment to reduce wrinkles on human volunteers, obtaining exhaustive and shocking graphical results. This same technology allows us to quantify protuberances and assess the anti-acne efficacy of a determined treatment. Colored maps of deep and shallow wrinkles, acne, uniformity, etc are included.
- Anti-wrinkles efficacy.
- Anti-rugosity efficacy.
- Anti-acne efficacy.
Whitening and Anti-dark spots
Using hyper spectral technology, we assess on human volunteers the capacity of a treatment to improve color uniformity, to decrease pigmentation of the dark circles, the number and the total area of the dark circles. 3D images and colored maps are included.
In the same way, we use Mexameter to quantify melanin and erythema levels.
- Whitening efficacy.
- Anti-dark spots.
- Self-tanning efficacy.
- Regenerative efficacy.
Face Volume and Contour
By using 3D Image Technology based on Structured Light, we capture different 2D images from volunteers and generate a 3D reconstruction from the area of interest (face oval). Comparing before and after a specific treatment, we can obtain data from area reduction, depth decrease and, thus, volume reduction of the face oval; from the mean deviation obtained in each of the analyzed points (whole of the face).
3D pictures in different formats are included for each of the volunteers.
- Styling efficacy on face oval.
- Slimming efficacy (face contour).
- Improve in face morphology (V appearance).
By using 3D Image Technology based on Structured Light, we capture 2D pictures from the volunteers, make a 3D reconstruction from the area of interest (neck) and compare before and after a specific treatment, obtaining data for neck sagging reduction (depth in millimeters) from the mean deviation obtained in each of the points of the vertical axis that crosses reconstruction.
This technique allow us to determine the efficacy of anti-sagging treatment, even though differences may be very small (millimeters). Images for marketing (3D and colored maps) are included for each of the volunteers.
- Anti-sagging (neck).
We analyze on human volunteers the capacity of a certain treatment to modify body temperature using thermal cameras combined with Infrared light. Ideal for anti-cellulite creams that activate the metabolism, massage creams, etc.
- Anti-varicoses efficacy.
- Slimming efficacy (activation metabolism)
- Sport efficacy (warm up).
- Anti-inflammatory efficacy.
Moisturizing / Elasticity / Sebum
We quantify on human volunteers moisturizing (corneometer), elasticity (cutometer) and sebum (sebumeter) levels of the skin, before and after the treatment. Tailor-made designs, according to client’s needs.
- Moisturizing efficacy.
- Firming efficacy.
- Anti-sebum efficacy.
Proliferation and Hair growth
We assess the capacity of a determined treatment or active ingredient to stimulate or inhibit the expression of different genes directly involved in hair growth regulation, regeneration and hair loss (IGF-1, KGF, VEGF, TGF-beta, Noggin, etc.). We extract hair follicles from human volunteers before and after treatment (in vivo) and compare gene expression through RT-qPCR, to assess the molecular efficacy and functionality of the treatment.
- Anti-hair loss efficacy.
Consumer Perception studies
Most in vivo assays include a consumer perception study. We analyse the subjective effects of a treatment on human volunteers, through self-assessment questionnaire, according to the client’s needs.
- Self-assessment questionnaire.
Gene or Protein Analysis through Tape-Stripping / Skin scrapping
We analyze on human volunteers whether a treatment induces or inhibits the expression of specific genes, obtaining cells from stratum corneum using tape-stripping or skin scrapping before and after the treatment. This assay is also used to determine penetration capacity in the skin.
- Molecular efficacy in vivo.