RESEARCH & DEVELOPMENT

The NanoCosmos project aims to create a European multidisciplinary network to promote the recovery of valuable bioactive compounds from plant by-products for applications in the cosmetics industry using nanotechnology. Funded by Horizon-MSCA (Marie Sklodowska-Curie Actions) under the staff exchange program, this project focuses on optimizing green extraction processes and developing innovative formulations for cosmetics targeted at sensitive skin.

Through collaboration between universities and small and medium-sized enterprises (SMEs), the project includes the participation of Bionos Biotech, which is responsible for validating the efficacy of the extracts obtained through in vitro, in vivo, and ex vivo studies. The project also promotes the exchange of knowledge between academics and industry professionals and encourages the training of new researchers, integrating them into the workforce through secondments and training sessions.

Bionos Biotech’s work focuses on evaluating the bioactivity and testing the efficiency of plant extracts such as chamomile, lavender, and saffron. These compounds will be used to develop more sustainable and effective cosmetics, contributing to the advancement of the circular bioeconomy.

🔗 Learn more about the project:
🌍 Website: https://nanocosmos.eu/

The AlgaeNet4AV project, funded by the European Union through the H2020 program, aims to characterize and exploit the biodiversity of microalgae to develop bioactive cosmetics with antiviral properties, particularly targeting pandemic strains of influenza and coronavirus. The project seeks to create non-pharmaceutical products that help prevent the spread of viruses, thereby reducing the risk and speed of transmission during pandemic outbreaks.

The main focus of the project is to investigate bioactive compounds such as lectins and polyphenols from microalgae, which have shown potent antiviral properties but have not yet been commercially exploited. Additionally, the project will work on developing more efficient microalgae cultivation systems, optimizing both the cultivation conditions and the production processes to increase the yield of desired compounds.

Native strains such as Chlorella vulgaris and Nannochloropsis oceanica will be used, known for their rapid growth and production of proteins and secondary metabolites. These strains have high potential for use in industries such as food, cosmetics, and pharmaceuticals, and the project aims to improve existing technologies and methodologies to reduce production costs, fully exploiting their potential.

🔗 Learn more about the project:

🌍 Website: http://algaenet4av.eu/

The objective of the SINUÉ project is the planning of precision surgical interventions guided by identity habitats of glial tumors, enabling intraoperative decision-making for immunotherapy treatment.

Development of a computational surgical planning system for high-grade glial tumors based on nosological imaging, allowing the visualization of key cancer characteristics in peritumoral regions. Additionally, the development of a digital PCR surgical kit for precise immunosuppressive characterization in the infiltrated peripheral edema region, enabling intraoperative decisions on immunotherapy treatments.

Project co-financed by the European Union through the Operational Program of the European Regional Development Fund (ERDF) of the Valencian Community 2014-2020

Bionos Biotech, S.L. has received funding for its project “Development of Screening Platforms for Drugs Against Huntington’s Disease,” with file number INNTA3/2021/26, through the Talent Promotion Program / L3. Business PhD Candidates (Innodocto) of the Valencian Innovation Agency (AVI).

This funding enables the training of a PhD candidate at Bionos Biotech, S.L., fostering the acquisition of the necessary skills to develop R&D projects in business environments and thereby increasing the company’s level of technical expertise and innovative capacity. Specifically, the project’s objective is the research and development of screening platforms for the identification of compounds with therapeutic potential for Huntington’s Disease (HD), which aligns with Bionos Biotech’s long-term R&D strategy focused on neurodegenerative diseases in general.

Microalgae biomass represents a highly rich source of compounds for the discovery of new entities and biomolecules. The industrial potential of algae-based ingredients lies in the ability of algae to survive extreme environmental conditions and thus develop unique adaptation and protection mechanisms. In this regard, algae produce a large number of metabolites, which can be sustainably utilized for the production of cosmetic, food, and pharmaceutical ingredients.

The AlgaeCeuticals project will leverage native algae species to generate high-value-added products through the application of novel omics technologies (genomics, transcriptomics, proteomics, enzymomics, and metabolomics), as well as specific cultivation techniques. To achieve this, AlgaeCeuticals will analyze and characterize a vast biodiversity of algae, develop and optimize cultivation systems, enhance omics resources, and establish efficacy and functionality evaluation strategies.

Reference: 778263
https://cordis.europa.eu/project/rcn/213018_es.html

PROJECT: ITTUTE/2019/37 – Bionos Biotech – Grant for the Check Internationalization Tutorials (Advice to companies 2019)

The main objective of this aid is to improve th strategy of sMEs in the Valencian Community in the different areas of internationalization and this, gain a competitive position in foreign markets through intensive, highly specialized and individualized support.

The project has had the help of IVACE within the program Bionos Biotech – Grant for the Check Internationalization Tutorials (Advice to companies 2019), with a grant of 2.520,00 €, with funding from the European Regional Development Fund (ERDF), through the ERDF Operational Program of the Valencian Region 2014-2020.

PROJECT: IMIDTA/2018/79 – “Development of screening platforms for drugs targeting Huntington’s disease”.

The main goal of the present project (HUNTINGFISH) is the reserach and development of screening platforms to identify compounds with therapeutic potential for Huntington’s disease (HD) according to the company’s objectives and long-term R&D strategies, in global neurodegenerative diseases.

The project has had the help of IVACE within the program “R&D PYME projects (PIDI-CV)”, with a grant of 31.622 €, with funding from the European Regional Development Fund (ERDF) in 50 %, through the ERDF Operational Program of the Valencian Region 2014-2020.

PROJECT: IMAPEA / 2016/43 – “New drug based on SOD-enzymes for the treatment of neurodegenerative diseases”.

The main objective of this aid is the preparation of proposals for the participation of BIONOS in the call SME INSTRUMENT-Phase I. The project has had the help of IVACE within the program PREPARATION OF PROPOSALS FOR CALLS H2020 with a grant of 3,542.50 €, with funding from the European Regional Development Fund (ERDF), in a percentage of 50%, through the ERDF Operational Program of the Valencian Region 2014-2020.